你怎么了?(以下几种皆可)
1、What happened to you ?
2、 What's come over you ?
3、What's the matter with you ?
4、 What's wrong with you?
【双语例句】
1、你怎么了?--没啥,有点头疼。
What's the matter with you?--Just a bit of a headache; nothing serious.
2、你怎么了?你为什么哭丧着脸?
What's wrong? why do you wear a long face?
3、你怎么了,一整天都病(病)殃殃的?
What's the matter? you look tired and sick the whole time.
医院里医生还可以问
What's your problem?
What's wrong with you?